Combined immunohistochemistry of β-catenin, cytokeratin 7, and cytokeratin 20 is useful in discriminating primary lung adenocarcinomas from metastatic colorectal cancer
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چکیده
منابع مشابه
Identification of relevant prognostic values of cytokeratin 20 and cytokeratin 7 expressions in lung cancer
Lung cancer is one of the most common malignant tumors harmful to human health. Cytokeratin (CK) is highly conserved and differentiated related to the proliferation and differentiation of epithelial cells. The aim of the study was to explore expressions of CK20 and CK7 and corresponding prognostic values in patients with lung cancer. Our study included 258 cases of patients confirmed with lung ...
متن کاملThe value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody
BACKGROUND/OBJECTIVE Metastatic adenocarcinoma from an unknown primary site is a common clinical problem. Determining the cytokeratin (CK) 7/CK20 pattern of tumors is one of the most helpful procedures for this purpose since the CK7-/CK20+ pattern is typical of colorectal adenocarcinomas. CDX2, a critical nuclear transcription factor for intestinal development, is expressed in intestinal epithe...
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BACKGROUND The vast majority of uterine cervical malignancies are primary carcinomas, and secondary neoplasms that metastasize to the uterine cervix from a distant organ are uncommon. Although relatively rare, metastases to the uterine cervix from a primary colon cancer have been reported. We report a rare case of metastatic carcinoma originating from a cecal adenocarcinoma with an unusual cyto...
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Primary sinonasal intestinal-type adenocarcinomas (ITAC) are defined on the basis of their morphological similarities to colorectal adenocarcinomas (CRA). Thus, differential diagnosis with sinonasal metastasis of CRA could be a real challenge. Neuroendocrine differentiation has been variably described in several types of adenocarcinomas and notably in ITACs and CRAs. In a series of 25 ITACs and...
متن کامل4 Cytokeratin 7 and 20 Agnieszka
Cytokeratins (CK or CKs) are the largest complex group of IF proteins. These are proteins, that are crucial in the development and differentiation of epithelial cells, as well as essential for normal tissue structure and function. The first keratin protein nomenclature was published by Moll et al. (1982) and it has been repeatedly updated in recent years (Schweizer et al., 2006). Based on the r...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2006
ISSN: 1471-2407
DOI: 10.1186/1471-2407-6-31